About this is actually the administration of ivermectin in a fairly heavy disease is feared at risk of causing neurotoxicity because the work target of ivermectin is glutamate-gated chlorine channels.
This allows ivermectin to be able to pass the mammalian central nervous system. The dose of ivermectin in viral research in vitro is also actually much higher than the standard dose of ivermectin for humans, so the effectiveness of the standard dose of ivermectin is still questionable in suppressing the SARS-COV-2 virus in vivo.
Normally, the ivermectin does not pass through the brain's blood nozzles. However, in the condition of patients with hyperinflammation, endothelial permeability may increase so that the drug can pass it.
But everything is applied due to emergency conditions and as a treatment law, there will definitely be side effects