Political instability - when political system in the country is not stable, everything will get down.
That is totally right. Many countries live under total political instability nowadays. It happens because we have a very splitted population inside a same country. Half of the population doesn't agree and wants the opposite of the another half of the population. It leads to a hostile climate, which affects the society negatively in all aspects: social, economical, professional, ethical...
One of the main consequences is the lack of interest from investors for those countries, because they don't know how it is going to be the next day, as they be affected by sudden abusive regulations. Since it's a risky deal to invest in such countries, they just prefer to move their money to places where they can find stability, a pacific society that literally speaks the same language.
Just like investors, bitcoin can be also negatively affected by those same regulations. I believe a solution would be if unstable countries were finally splitted in half or more, like the old kingdoms of Europe, so each citizen could live on the territory he agrees with the political spectrum.