A large amount of investment or loan investment is very risky. When the market changes and the price drops, you must bear greater risks and economic losses.
I would say that taking out a loan is the worst idea to get started with an investment in cryptocurrency, especially for altcoins (no matter how much confident the user is). But all that said, I know at least two guys, who took out a loan to invest in cryptocurrency (many years ago) and made huge profits out of their investment. But it is entirely another topic if someone want to take a similar step at current levels. The risk factor has gone up by manytimes, and I would definitely disapprove of taking loans to invest in cryptocurrency at this point.
Some investors may have studied and studied the projects to be invested and market trends and have their own investment plans and strategies. They will have great confidence in loan investment and profit.
But now many investors will choose to invest blindly, they will have a relatively large risk when investing in loans and have to bear relatively serious economic losses. Therefore, loan investment is a very risky choice.