The whole point is, when every form of life has been killed off, nobody will need vaxxing for anything any longer.
You'll know it is getting bad when they start vaxxing the dead. I mean, vaxx your table, because it was once living wood.
But, seriously. If he people won't accept the vaxxes, make sure the farmer can't get his subsidies until he vaxxes all his animals, with a vaxx that can be passed on to anti-vaxxers.
