What do you think Wilder will do next to try to salvage his career now?
The only way he can fight for the heavyweight titles now is by becoming a mandatory challenger and that can only happen if he wins a couple of comeback fights.
That's the only way he can be a champion again, go on and fight other heavyweights and make a good impression that he can be fight as mandatory, otherwise his career is over. It might take a long time though for him to recover from this lost.
Does Wilder even still have it in him to retain a high level of dedication now after Fury showed him over 3 fights exactly how inept he was when confronted with a superior colossal fighting machine (in Fury).
Again, to bring back his confidence, he should fight b-level fighters knock them out. In that way, he can feel good about himself. The road might be long, but that's the only way he can bring back his mind to become a champion again.