I like Binance and Bittrex best. I like their site better. Affiliate system is also better.
These two exchanges can be traded safely. I tell everyone to use these two exchanges. They have lower security and transaction fees.
I left trade on Bittrex because many coin have less volume transaction and right now only Binance and Hotbit as platform exchange for my trading and investing. I think if you want to get much profit could check with new coin listing on Kucoin, I see there like Hotbit when new coin listing can pump 1000% but few hours later price back dump drastically, take risk with higher profit is better than few percent only.