Meme coins are very volatile - that's their advantage. I would suggest you to gamble with them with a small amount of money. If you lost 100 USD - it's not a big disappointment for you. But if you got +500 USD after risking with this 100 USD - that looks great!
Guess the amount isn't as much a problem as percentage of portfolio. To one person $500 is nothing to lose where as others it is. What people should follow is don't invest more than a minute portion of your stack in meme coins. So if all you have only $200 to put in $100 is a lot. In general steer clear most will get their money swiped and encourage "devs" to make more meme coins.