In general, the common ground that affects and positions at disadvantage/risky side all of the three kinds of people you have mentioned is volatility. The fluctuation of market price is definitely the main factor that could risk one's asset. It's the nature of crypto and we are all aware of that. It just depends on how we will manage and cope with it to our benefits.

As a retail investor, the volatility could affect your decision making in investing. There are times that the position is low or high depending on market demand. Sometimes, the price value of bitcoin in the market seems to be 'low' but it isn't it. And if you happen to invest in high position, you'll have a feeling of regret later. Since you can't really withdraw it after a while. You'll have to wait for the price to climb. Personally, if you're an investor for long term, I guess volatility brings you less risk. Unless you will be FOMO-ed.

As an asset manager, the volatility could make a huge impact to the account holder's portfolio the moment things go the way you perceived it to be. If ever things don't happen like what you predicted, you will be in a trouble. So you have to always have a plan B as a way out before it's too late.

As a trader, volatility could either make or break your asset. You should always watch the chart trend of pump and dump and do technical analysis as a basis of your decision. You should know when to take profit and when to cut loss. If ever you'll just hope for the best despite seeing that the position is going nowhere, your assets will be liquidated.

There are so many keypoints that I haven't mentioned here yet, but these are the things that first came into my mind. Hopefully, I gave you helpful insights.