You can win but if you want to beat the house its never possible because the room will take certain percentage as commission from each hand but they are not investing anything since poker is pvp not player vs house unless its blackjack. Rake fee is literally less in the online casinos so say thanks to the crypto casinos instead of trying to win them since you have to pay a lot and lot other expenses if you are going to an offline casino...
I don`t think that percentage will be more than profit. In this case it makes no sense to play against the house and no one will play. Surely you play rake but it can`t be more then maximum profit you can get from the game. But as we discussed before - the profit is too small to try to get it. And pvp playing of course more interesting.