Trading with leverage is just an option you can make a trade with low leverage or zero leverage but if you have a small amount of money only and you want to make a trade its not profitable at all, else you will put leverage so you can get a higher chance of profit. Always make a trade which you can only afford on it. Lossing a trade does not mean you lose a profit still at the end of the day number of earning on every trade is the one you gives a good outcome. So base in my experience safe leverage is with the range of 25-75x.