Pi4 might be overkill for it if you're trying to save a couple bucks. You can probably get away with a Raspberry Pi 3B+ which is a bit cheaper and just SSH into it. I haven't tested 12+ sticks on mine yet but i think it should handle it no problem. I have a Pi 3B+ Model A that i'll try out and report back on.ting like 3.5-3.9 TH/s off 12 Compac F's.
When the R606's came out I tried the Pi 3b and had terrible performance with it. I moved up to the Pi 4 and that works great.
Just my $0.02 worth.
Was it the 3B or the 3B+? Not sure if there's much of a difference spec wise but I am running 2 R606's with 5 Compac F's & 2 newpacs on my 3B+ at my family's house with no issues. every once in a while (like once or twice a week) one of the R606's stops hashing and you just need to plug/unplug the USB from the Pi but otherwise it runs smooth. Pushing like 3.5 TH/s there on a headless Pi.
Roughly have the R606s @ 800-1000 GH/s
Compac F's @ ~300GH/s
Newpacs @ ~100 GH/s