ASICs will impact some coins, but there are ASIC & Multipool resistant coins as well. If they take hold then GPUs can still compete well through 2014. I just switched one rig over to Vertcoin, it does take some time to get the settings right for 0 HW errors.
Most of my hash power is directed at Scryptguild currently, because I hold onto LTC also. I didn't see the option on Clevermining or Wafflepool to hold any altcoins at all.