I have been thinking about this for sometimes.
If the metaverse becomes a reality, what will be the significant roles of crypto in its economy?
If crypto such as bitcoin, Mana, Sand are used as means of transaction in the metaverse what will be the reaction of the government?
Metaverse is a virtual universe and bitcoin is the best currency of the internet. People will either use ETH or BTC as their main payment method. BTC is slower and more expensive than the others sometimes but since it is the safest, it will always be used the most by the people. I don't know what Mana and Sand are all about though but I don't think they will be as popular as BTC.
You never know whether by the time that met averse becomes a reality there might be a cryptocurrency more suited for the usage within that ecosystem. But keep in mind that Zuckerberg will be one of the major players in making the metaverse develop and grow. He is heavily investing in AR and VR, but he is not the biggest Bitcoin friend. Instead, as we remember, he wanted to establish his own digital currency and I can imagine that is still working on that plan. I guess if he runs a lot of the metaverse infrastructure he might also have possibilities to at least suppress the usage of Bitcoin to a certain degree (or provide incentives to use his stuff).