I've had a competitor's card for nearly two years now, and it's really soured my opinion of crypto-backed credit/debit cards.
Never understood the appeal of these things. A good credit card that's accepted everywhere, 1-5% cash back, grace period, etc, works great for fiat purchases. Then I can pay the monthly bill by selling some corn if I'm so inclined. Much easier for tax returns too, ~12 transactions instead of hundreds.
Well, in case of Ledger card your crypto will be on your hardware wallet and not on the exchange.
Most likely you'll have to move it in order to use the card. So that probably means funding the card in advance or carrying the HW wallet with you along with the card.