I didn't understand your question but I am thinking that you want to ask in which coin you get a big loss. and my answer is ENJ I bought ENJ in 4$ per ENJ now it is the price is 2$ per token 
As for the example of loss, I think there are lots of coins that you can mention here, but if you refer to the OP's question then there are only a few coins that are suitable to have as long as you have enough patience to hold them until you are profitable with them.