Uniswap
Uniswap is a decentralized exchange and got popular when it launched.
Until now, Uniswap is leading internally for decentralized exchanges.
Decentralized exchanges have multiple advantages like a very easy access, a democratic surface because we don’t need to trust a middleman. Uniswap is only based on code. Uniswap is permissionless because people don’t need permission to use it and Uniswap does not need maintenance fees.
Compared to Binance, Uniswap is much better.
Yes, Uniswap will flip Binance because Uniswap is easier to use.
Uniswap has a very high chance to replace Binance and profits of Uniswap can be huge.
Swap fees on Uniswap are very high, of course this is not an easy thing to beat Binance. BNB is also used in many DEXs like PancakeSwap and it provides very low fees, so it's really hard for Uniswap to beat Binance in my opinion.