There's nothing wrong with getting some gains.  I try not to sell, but as a longtime holder there have been times when Bitcoin makes up an uncomfortable amount of my net worth.  There's no point in losing sleep over volatility, so I think it is always good advice to have only what you can afford to lose in crypto.  If you're losing sleep over the volatility, you own too much.  I also think it's always best to pay off debt before speculating too much with investments, so that should always be your first priority.  There's nothing wrong with selling your BTC to pay off all your debts, and then beginning the stack again.  Life gets a lot easier and less stressful when you're debt free and diversified.