Looking at the current Premier League standings, it is difficult for me to predict who will be in the top 4 at the end of the season. Because the difference in points between Manchester United, Westham, Arsenal and Tottenham is very close, even from the 8th position which is now occupied by Wolves is only 4 points. If one of them fails to win, it will certainly change the standings. This makes me excited to see this competition.
The victory over West Ham made the Manchester United players very happy because the addition of 3 points made them managed to climb to the top 4 of the Premier League. Now who is the candidate for the English league is no longer the main topic, The reason is that Manchester City can certainly win the English Premier League for the 2021-2022 season.The media are more focused on who will represent the Premier League who will qualify for the UCL next season.
West Ham, Arsenal, Tottenham and Wolves have the same chances as Manchester United. Their points are quite close, Mistakes in 1 game will make changes in the standings.
Tottenham benefited a bit, because they've only played 20 games, but not a guarantee for Tottenham can finish in the top 4 at the end of the season. It is quite difficult to guess who will occupy the top 4 positions, but it's very exciting to see the struggle for position 4 until the end of the season.
Some teams do have some postponed matches, but still that can't guarantee they will occupy the top 4 positions at the end of the season, now the teams fighting for the top 4 must be able to maintain performance and consistency in their game, because as you said , if they lose poin in just one match will automatically be an advantage for the other team, and make their chances of reaching the top 4 will be even more difficult.