It is likely that in 2022 there will be an opportunity to buy BTC and ETH at a good low price, but you need to guess when the final fall of the crypto market will be. As you have already noticed, the market has recently experienced a good fall and it is likely that those who managed to buy BTC and ETH at a lower price and now make money on it. What is still swinging such falls, that is, there is a high probability that they will be in 2022 and more than once. Perhaps it is at these moments that you will need to buy BTC and ETH. As for triggers for such falls, they can be the same negative news about cryptocurrency.
We are already on the year 2022 and yes there is a buying opportunity right now because almost all cryptos are in heavy dump but to predict if when is their bottom is something that is hard to do not unless if you have a special powers which are also unlikely.
How can you say that they are in profit when they also bought at low? What can actually happen is they will loose huge if they do that. That is not how to play the crypto game but it should be buy low and then sell high. Apart from the natural fall of eth, there are also bad news that are coming lately from this coin so I do not really recommend eth for the long term but you cannot go wrong in bitcoin.