Without a doubt you are going to need a piece of software to take advantage of arbitrage opportunities as it is impossible to take advantage of them otherwise, however do you have the capital to pull this off? Arbitrage trading can be profitable but since the profit of each trade is low and you need to have several accounts in different exchanges then the amount of money needed to become profitable is incredibly high, so unless you can fulfill this requirement then you should forget about it for the time being.
I remember the time when it was possible to do without a bot for arbitrage trading, but now everything has changed and it is impossible for you to do without bots to get a profit. With such volatility in the cryptocurrency market, you can make a profit without wasting time on arbitrage trading.