Sure!

I have a rig that have 2x rtx 3080 non LHR (different brands, and settings), 1x Radeon VII, 1x rtx 3060 LHR1, and I can mine under win10. I try one miner (Phoenix, Team Black) for all cards, and that try one miner for the nVidia cards and one for the Radeon VII (team red). All try works, but for me one Phoenix is the best. And I mine monero in this rig with CPU., and farming Chia with HDD. Everything works

Joz