It depends on how much you bet and where you want to support. In sports gambling of course you need to take a time where is ideal to make a bet like having research on the team, strategy, best plays and current lineup. When I make a bet too I do a single bet because at that time I can now watch the current live game and don't need to pressure too many indifferent bets. If you can handle in different game good but if you want to watch those games and get entertain go for a single bet at the end of the day still profit is the ideal thing.
I just had to smile on reading the highlighted part of your comments. Using the recent match between Real Madrid and PSG as an example, predicting a win in that match was a difficult task. Real Madrid has a reputation with some top players such as Mendy and Benzema, while PSG has players such as Messi, Mbappe, and others. You may strategically want a win for PSG or a draw, but who will believe Messi will miss that penalty? It would have been a different story if Mbappe hadn't scored the ball in the final minute.