Like you said, coins at top 100 has the potentials to grow whenever btc goes uptrend because of their popularity which contributes to their good market cap. The ones that go down are mostly the meme coins which has no sensible use cases.
Coins that are on the top 100 did not land there for anything they have investors' support and they have proven their worth in the market, if you have a new coin that is struggling to move because of lack of volume and lack of development you have to think twice and move to another coin, some coins are worth holding on, you can be patient but there should be a limit on how patient you are on your investment.