The odds doesn't change that much, Donaire is still 4:1 underdog.
I think for underdog bettors this is really a good odds assuming that Donaire can still fight and has the power and the timing to counter Inoue when he is going inside just like in the first fight. Donaire though will need to have a lot of stamina against the young Inoue to be able to sustain his attack the whole 12 rounds because this is what I'm seeing in this fight. Back and forth war throughout 12.
The only chances i can see for Donaire to get the win is to either control the early rounds or knock Inoue down even once and then calm down and just defend on the late rounds. I mean Donaire's style of play tends to be aggressive on the early round and then gas out on the later round, causing his punches became weak.
Inoue is known to have a destructive punches, if Donaire gas out on the later round he'll most probably gonna make that as an advantage.
We had already see on how Donaire had gas out on later rounds which is something noticeable and because of that you would really be likely to lower up your guard most of the time or you arent already on your tempo
thats why solid body shots could be on the way which would really be taking you down if you arent that attentive but well at least he had able to finish out it for 12 rounds but we know that he do fall short.
IF he do able to overcome that weakness then he might be having the chance, tending to knock Inoue for early rounds? I would see that this would really be that hard to achieve.,