I'm assuming you're using the BitcoinMerch USB hub:
https://i.imgur.com/tFIqfJi.jpgThat USB hub is quite alright, much better than most, but it has a limit of 2.4A per port. You're hitting that limit when getting towards 400MHz, so try setting it a bit lower, say 380MHz or so. Note that it might be the combined power that is tripping the hub as well, so check your power supply to see how much it is providing. Experiment with different values per miner. You should be able to get up to around 480MHz with a single miner connected.
You can confirm this by connecting one of those cheap USB measuring devices like this one:
https://i.imgur.com/X5haK6Y.jpgKeep going up towards 400MHz and you'll see that when it reaches 2.4A it will reset.
It's really difficult to find a USB hub with data and power with more than 2.4A. The recommended one is the GekkoScience USB hub which is custom made for USB mining. It's pretty expensive and hard to find though.
https://i.imgur.com/C70ERqM.jpgThat one will allow you to go higher than 400MHz with no issues.
If you do manage to get that one, make sure to have excellent cooling as it will get really hot.
Yep I'm using that hub from Gekko. What does the difficulty setting do? Should I be adjusting this or just leaving it as is? Mine is currently set to 442.
Also, am I able to issue a command to the sticks while actively mining to increase the frequency and/or difficulty? I've been closing out my console to do it, but I'd like to keep the session open while issuing another command if possible.
