Villareal will not easily beat Barcelona even though they are no longer concerned with points to qualify for the Champions League next season. Barcelona are already safe to qualify for the Champions League, but they also don't want to end the season with a loss to Villareal.
Barcelona vs Villareal and Sevilla vs Bilbao matches in my opinion will be very interesting because one of the away teams will ensure themselves to qualify for the European Conference League next season. Sevilla shouldn't be losing at home, and neither should Barcelona.
My prediction is that Villareal will lose to Barcelona and Bilbao will win against Sevilla. All teams will give a good game at the close of this season. I will not feel guilty if Bilbao will be the Team that will compete in the European Conference league qualification. And in another match between Cadiz and Alaves I will bet on Cadiz win and Cadiz deserves to stay in Laliga for next season.