My prayer just goes to Manchester United, I don't really want them to go Europa conference league. Manchester United is too big for that.
Yeah, it's a bit strange to see Man United competing in the UEFA Europa Conference League, however, it could really happen if Man United can't win against Crystal Palace, while West Ham can beat Brighton. Even Ronaldo reportedly will not be able to play because of injury problems, and I think this will affect Man United's performance.
The Premier League this season is really competitive. The determination of which team will be the champion and which team will play in the Champions League and Europa League can only be known after the season ends.