Defi, NFT and BST are the coins that will be in the limelight for 2022 as they are spearheaded by a team of experienced developers/engineers who have proven their skills after various successful projects and don't want to see such successful projects fail.
The fact is that Hype Defi and NFT have failed for now, you can see Luna and Axie being sold on NFT with falling prices so be careful holding long term hype coins, you have to stop investing on hype but sometimes only for profit from scalping because of hype projects get great enthusiasm when big news is announced, but it will be risky so better invest in Bitcoin and top altcoins.