It's impossible to say who will win the 2022 World Cup Qatar, but history shows that the CONMEBOL confederation has won on the Asian continent. The weather aspect will play a huge role, and the scorching temperatures in Qatar, in particular, will be difficult for European players to adjust to. When Brazil beat Germany 2-0 in the 2002 World Cup Final at the Yokohama International Stadium in Japan, it showed that the CONMEBOL Confederation's team was more tolerant of the Asian continent's weather, despite the fact that the UEFA Confederation's team had won the World Cup 12 times while CONMEBOL had only won 9 times.
The tournament will take place during winter season (November-December) and by then the weather will be more tolerable. December daytime temperatures hardly goes over 25 degree Celsius, and during nighttime, the temperature can drop to around 5 degrees. So there will be no added advantage for the AFC or CAF teams. Anyway, almost all the teams that are taking part in the tournament this time are having the experience of playing in GCC nations. So I don't believe that any particular confederation will be having an upper hand.
I'm relieved to learn that every member of the National Team has an equal chance of winning the Qatar 2022 World Cup, as the weather will have no bearing on the team's performance in November and December 2022. The FIFA rankings should not be used as a yardstick for a national team, in my opinion, because each match at the Qatar 2022 World Cup will be difficult to win.