St Pauli vs Nürnberg looks like the top game considering the ranking of the last season. This might end in a draw. It is a bit random to look for a best team after one match day, but I think Kaiserslautern and Darmstadt will win their games and potentially taking the lead.
For the whole year, it might be finally the time for Hamburg to reach a spot in the top2 and to go back to the Bundesliga.