I think the clothing department will take every step necessary to make sure that the players play at their 100% in every match.
But, the change of location and weather is always going to affect any athlete at any time. often we forget about the Jet lag which at times can prove to be a really bad thing for any player. But that obviously does not affect the players directly as the weather does. I don't think it will be that much of a problem because most of the players are used to playing in different conditions.
Asian region in the Middle East has quite hot weather and a challenge for players who are currently actively playing in the European zone, they will have difficulty adapting to hot weather conditions. Weather in Qatar is currently 44°C and the organizers have to postpone the match until November 22, 2022 so that the weather in Qatar is not really hot. Maybe little disturbed by the world cup event which is usually held at the end of the competition break but this time when the competition or league runs for about 10 weeks. Usually on June have held FIFA World Cup match but when choose Qatar with hot weather have change all schedule where usually held. I think not bad because all player will adapting with new schedule regulation.