There is both a difference, and there is also a similarities between them. First of all, Mona Lisa has a value right?
Note that there are different kinds of values. There's market value, personal value, intrinsic value, objective value that's measured with usefulness etc. Mona Lisa does have a high value, but not necessarily intrinsic or objective. On the other hand, bitcoin does have usefulness and IMO, its objective value is higher than its market value.
Mona Liza and bitcoin is not a good analogy, in any case.