Taking of profits should always be done when you're being privileged to, that's why you should always set your stop loss and take profits, when it hits your target the trade should automatically close by itself, many before don't set there targets because when it pumps or when they see little profits, they don't take close the trade, they will want it to pump higher and more that only greed can cause them to do that, and by so doing they're exposing themselves to more losses because crypto isn't something you made a $1m with just $10 in a day, it's a gradual process so I'll advice you follow it up accordingly.