For me the biggest pro and con of bitcoin gambling is the same thing: its high value and high price appreciation. Bitcoin is constantly going up in value if you look at the lows over a 2-3 year period so it';s the best coin for saving money and holding for the long run. If you gamble it away and it gains value next year you're going to feel the hurt. The same thing is also a positive feature because if you can win some and hold it you're going to be very happy after the next halving.

If you know what you're doing and usually win, bet whatever you like. If not, choose a cheap altcoin especially one of those that you can get for free