With a current share price of $273.70 and a Bitcoin value of $332.27 per share, you can see that they are also using debt of which they currently have 2.44B.
The debt comes to $261.52 per share. They also have around $10 in cash per share, so we'll say there's $250 worth of debt and $330 worth of Bitcoin for every share of Microstrategy. That means with no leverage (they are using a little) and no profit (they had profit of over $400M last year), you would expect to see the stock trading at around $80 per share. This shows the market believes greatly that Microstrategy will continue investing in Bitcoin and that the Bitcoin price will rise. Perhaps I'm overlooking something with my quick calculations, but it seems that GBTC gives you more BTC than you pay for, while MSTR gives you far less. The difference being that GBTC has to sell BTC to pay management fees while MSTR buys BTC with income.
Most companies have debt to assets of around 70% too so that makes sense as a figure - it could be a problem if btc falls to much but given the earnings anyway it's probably not much to worry about as they have other assets/services too.
I think net income is normally used instead of gross profit to work out how much a company has made (based off gross profit, their margins look high though - as if they're quite far in profit - net income includes other things like taxes though I'm not sure of its name on US balance sheets as it might be different).