when mixers use vanity addresses.. they are not really helping to hide peoples activity (eg chipmixer)
when mixers request users deposit exact allotment of coin this pattern highlights them as a mixer which has a certain allotment pattern. again not helping hide users.
when regulations tell businesses to watch any/all users of mixers. which means red flag users of mixers. then the very act of using a mixer becomes anti-privacy. because those who dont use privacy tools dont get a red flag and thus dont get put on a watch list.