Multisign sounds like a huge benefit. As far as I'm aware every company that does Internet banking currently needs 2 signatures to transfer money. One from the finance guy who actually works out what to send to who and one from management who should verify the finance guy isn't transferring the money to his personal account.

Also using this for escrow saves us from the serious problem of having to trust the escrow organization.

However more complex solutions carry a greater risk of failure. Using this means there are now more ways to lose access to your coins.