On paper, Germany and Spain can be said to be the seeded teams in Group E. However, anything can happen in football.  Likewise, Japan and Costa Rica are ready to block the journey of Germany and Spain in the group stage of this World Cup.
Hansi Flick's squad is filled with experienced players and young players such as Serge Gnabry, Jamal Musiala, Joshua Kimmich, and Manuel Neur, they have a fairly even squad depth in all lines.

On the other hand, Luis Enrique's squad is filled with experienced players and quality young players with an average age of 25 years, one of which is Ansu Fati who is a very talented young player.  In the last meeting between Spain and Germany, the German squad was defeated by a score of 6-0 in the UEFA Nations League match.
despite all that, after all Germany and Spain are tough opponents in the world cup this time, however, another squad is more favored to be a candidate for the 2022 world cup champion.