Unfortunately, knowledge won't be enough in trading; it would be an advantage but it won't guarantee profit always. Even skilled traders suffer from losses, simply becaude the market is unstable in nature. TA's won't be a help whenever the market is going "crazy". Strategies would also help but for sure, luck will play a huge role in order to be successful in traing or even with other investments.
Really though, as with cryptocurrencies, the trick is to not TA but instead trade narratives and be early on them. e.g. Being early on "GameFi" in 2020-2021 and such. People who bought AXS very early on made a huge killing.