Roma's chance of winning is still there in this big match considering that Inter's condition is not good now and Inzaghi is now in almost the same position as Allegri who is unable to sit still because of the results he has achieved so far.
The defeat against Atalanta must be used as a reference for them to rise again now because with that they can become more confident.
Among the renowned and big teams in Serie A, the weakest and most unstable performance is that of Inter Milan. Out of 7 matches, Inter Milan won 4 matches and lost 3 matches. They lost against Udinese, Milan and Lazio. And Inter Milan has been able to win against relatively weaker teams. In the next match, their opponent Roma is not a weak team. Inter Milan will definitely need to get back on track against Roma if they want to win. And of course, the defense needs to be strengthened. Inter won't be able to get 3 points against Roma if the defense is weak.
Right now maybe with Roma's current condition the statistics in the match will be different especially if we look at the current condition of Inter which although managed to bring some victories but that is only a small part because as you said it is a relatively weak team.
Especially if you look at Inzaghi's current condition, which is not very comfortable in the coach's seat, I think this will make a difference.
The victory of one team will change everything both in the standings and in terms of confidence.