There is no doubt that Barcelona has been playing extremely well most recently, and they are in a very good position in La Liga right now. Unfortunately, they don't have a good record in the Champions League competition, which is what makes the problem worse. It is for this reason that I believe they will be unable to win the match against Milan in the upcoming match. However, the current form of both teams, makes it apparent that it looks like Barcelona is going to be the winner of this match. In addition, Barcelona also lost against Bayern Munich in the Champions League very recently as well. Therefore, they will also be determined to do well in this match as well.
The problem now is that some players can't play for them and it's confirmed that Kounde and Araujo can't play now.
Kunde is expected to be out for the next 4 to 5 weeks due to his injury and Araujo is more severe and is expected to be out for 8 weeks for Barcelona.
Obviously this is a loss for them because indeed these two players can be considered vital in their position.
Surely now these injuries are the biggest concern for Xavi and Barcelona because they are going to suffer badly with these injuries and performance is also going to be decline because these were their first choice players but right now we can't do anything for this just wait for have better updates about availability of these injured players which are going to be out of the game for more than 4 weeks with Kounde and Araujo is already confirmed but reports about De Jong are coming which will give better update about his availability.
Now they need to be gone with their second choice players until these recoveries which are surely going to have big impact on their performance in big matches specially against Inter Which is coming shortly in Champions League.