Businesses in poor countries tend to face greater challenges and obstacles than those in developed countries. This includes factors such as a lack of access to capital, limited infrastructure, corruption, and a lack of skilled workers. As a result, businesses in poor countries often have a lower success rate than those in developed countries.
I see as a major difficult in developing countries the fact people don't have much money to spare, so you as a business owner have a very limited customers' base to acquire your services and products. People are too worried about survival that they will only have access to basic goods and in a limited scale. Furthermore, even though there aren't customers for everyone, the concurrency is the same or even more expressive than in developed countries. There are too many sellers for too few buyers. This situation has a very negative impact on individual businessmen and many consequently have to close the doors at some point.
That's why I made the other point, only locals can run a successful biz in poor/developing countries.
They have experienced the poverty and can make more accurate assumptions when it comes to people's spending ability & related projections. Unless you have millions to burn and can keep on adjusting the scales until you start making some profit.
This is what amazon did in India. They had billions to burn and seized a major chunk of E-commerce market while parallelly figuring out a revenue model that works.