Real Madrid will have no difficulty facing Osasuna moreover they will start the match at the Bernabeu. Real Madrid will win the match easily because the quality of the players Real Madrid has is better than Osasuna. The international break will not make Real Madrid's quality decrease even though some Real Madrid players have just exhausted their energy to defend their country. I think Real Madrid will party in this match, my prediction is Real Madrid will win 3-1.
There will be no big problems for Real Madrid in this match. They will continue their winning trend in this match. Osasuna is not a strong opponent, just don't underestimate it. But Real Madrid has its own way of winning games. I wouldn't be surprised if in this match Osasuna scored first. Because at the end of the day it's a game that Real Madrid will comfortably win.
I use to advice not to take any results for granted, and not to underestimate any rivals neither. But, in this case, I would dare to make an exception and bet for Real Madrid, as it is a clear win to me. And don't take me wrong, I like Osasuna, and they are performing really well this season (fifth place so far is a really good result for them), but because of that, Real Madrid will be well prepared and it will be difficult to catch them off guard.