I think everyone has been talking so much about how Barcelona's poor talent pool or 2nd lineup in case of 1st lineup got injuries. So far, I haven't seen Xavi try to address this.
I don't think players' injuries will really affect Barcelona's performance in the upcoming match, Barcelona have some good substitutes both in defense and in midfield. Araujo's injury will give Pique a chance to play, as will De Jong who may be replaced by Kessie. This season Barcelona have a lot of options for players in defence, midfielders and attackers and I think that will really help Xavi keep his team form this season when their main player is injured.
Barcelona's main and second line-up this season is good, so I don't think there will be big problems in the next few games even though a busy schedule awaits. I want to focus on the match against Mallorca, so I don't have much reason to worry about the possibility of Barcelona failing to get the 3 points.
I am sure Barcelona will win easily in the next game. Their team is now one of the favorites in the tournament. However, Barcelona may face some problems in the El Clasico match. Because some of their players are already injured. Those who always play in the starting eleven and their roles are much bigger. If they can't overcome injuries before El Clasico, I think Barca will be in a bit of trouble.