Napoli were really good at UCL this year, we've seen that in both games they've played. Ajax is a young team with a quality squad, but they lost Anthony compared to last year. This greatly reduced their attack power. They also sold Haller, last year Haller had a phenomenal performance. This year Haller is unable to play in Dortmund due to health problems. As for Napoli, they will be able to beat this Ajax.
I think so too, because Ajax no longer have Anthony who has played at Manchester United this season. But if you look at the Eredevisie, Ajax are also competing very well and their position is not so bad in the standings. But because this is about the Champions League, Ajax needs to improve better because Napoli themselves are still very consistent until now, both in Serie A and in the Champions League.
Napoli and Ajax Amsterdam played quite well in their respective domestic leagues. But as you said this is the Champions League they need to do better. It's not meant to rule out the domestic league, but indeed in this Champions League the competition will be tougher and tougher. I also predict that Napoli will be a superior club compared to Ajax Amsterdam in this match.
Opportunities for Ajax Amsterdam are still very wide open to see the appearance of competitors Liverpool at this time. That's how they can make good use of it or not.