at some countries that gambling platform suspend especially from muslim countries , of course it will be serious problem , by regulation their position become more weaker. government and another stake holder that rellated with gambling statue will directly cut all access to this site. but for countries that allowed gambling platform , by this regulation they will parallely adopt bitcoin and also have legal standing.
Well if Eastern countries are prohibited gambling at all, the casino just need to avoid to serve on Eastern countries only. Why in the hell Eastern countries want to gamble? are they not scared if the government trace them and put them on the jail since they broke the laws? it's inevitable since you're using a centralized server of your internet provider. I'd say even though there's will be few people from Eastern countries are gamblers, they're not contribute much money for the casino.