There's nothing happening with gambling projects if crypto will be regulated. Im sure that the regulation will be putting its focus into the taxation for crypto users and AML. The gambling platform just need to follow what will be did by regulators. It's quite easy to follow the regulation.
I think this will not become a serious problem for the platforms that are also supporting the crypto.
It will not create a problem as long as the gambling casino is transparent and has no hidden reason on taking an advantage over their players. However, with a lot of regulations around, I guess casino operators will be more pressured and will have less chances to maximize their profits as government will always ask for their share like putting taxes on every deposit and withrawal made in the casinos.