Next time the lead might change hands in the standings. Because there are matches like Roma - Napoli and Atalanta - Lazio. In case Atalanta win and Napoli lose, the new leader would be Atalanta. However it is really not easy to see this. Even though Roma are in a pretty impressive shape and they are playing home, Napoli are still a huge threat to them with their form. You must be remembering the Milan - Napoli match which Napoli defeated their opponent. Maybe they can do the same to Roma also unless Roma become very careful.
It isn't easy for Atalanta to win either. Lazio are one of the strongest teams of the recent weeks. I wouldn't be surprised if it ends in a draw.
Roma have shown an improvement in their performance. but to fight with Napoli won't be so good for them. Napoli are much more consistent and of course have better confidence in facing Roma. If Roma manages to end the match with a draw, it's good IMO.
Roma are in high confidence ahead of the match vs Napoli, they have just managed to move up to the top four after beating Sampdoria last week. When it comes to consistency this season, Napoli is more consistent than Roma. Roma victory over Sampdoria was also lucky from the penalty spot, they didn't play like the Winning team against Sampdoria.
Despite playing at the Olimpico, it is very difficult to predict Roma will win this match because Napoli's performances this season have been very consistent and they are very difficult to beat. A draw may be obtained by Roma despite playing at the Olimpico because Napoli are one of the strong teams this season.