Casimero is still too young for retirement, though I agree that Casimero has no room for a loss in this match, or else he will be another piece to the Akaho Collection of beaten Filipino boxers.
But if ever Casimero loses this match, it just shows that likely, he doesn't have the skills and power to compete at the top rankings or a title match. Casimero is 32 years old and if he will experience continuous loss, it will just put him below rankings or the worst not even considered to be assigned now on any match. It's hard to climb on rank and that will take time as we are not even sure if Casimero can average 1-2 fights per year at the point of his career.
Anyways, let's not talk about the possibility of Casimero losing here because the winning probability for him is decent. However, upset does happen but unlikely not in this match. If this really ends up with Casimero losing this match, I should also say that he needs to hang his gloves now.
Speaking of Casimero if he'll get defeated this time although it's very unlikely to happen, just like you said. But if in case that happens, I don't think he have a future in this industry anymore because where will he go next? Bantamweight doesn't fight him as he'll be having the same issues again and in the upper weight class, he can't give some troubles, so it's much better for him to retire. But just like we said, it's very unlikely, especially now that he himself is looking to bounce back to redeem his name again.