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Or do something more complex with fewer keys?
like what? what would someone be needing to do exactly? other than make a vanity address or crack a bitcoin address.I don't know why we're having this discussion; Python performance is not something to agree or disagree about, you can also have a look here: https://medium.com/swlh/a-performance-comparison-between-c-java-and-python-df3890545f6d
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The same program in C or Rust can easily run 10-100x faster; so instead of 3 months a program would run for a day. That's quite significant.
i'm sure the cpu makes a difference too. get a high end cpu and run python on it and it will be just as fast as a low end computer running c. there's optimizations to be made everywhere not just in software.
On the same hardware, it's still slower by the same factor as before..